National Institutes of Health · USA

A Holistic Approach to Study Non-Addictive Natural Products for Pain Management

Vorankündigung — Öffnung erwartet am 2. Februar 2027

Dies ist eine Vorankündigung: Der Fördergeber hat die Ausschreibung angekündigt, sie ist aber noch nicht geöffnet; Veröffentlichung voraussichtlich um den 2. Februar 2027, voraussichtliche Frist 25. Mai 2027. Antragsberechtigte Gruppen laut Quelle: County governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses und 12 weitere.

Frist: Voraussichtlich 25. Mai 2027 (noch nicht bestätigt)
Öffnet: 2. Februar 2027
Fördersumme: Nicht angegeben — siehe offizielle Ausschreibung
Förderquote: Kein Pflicht-Eigenanteil angegeben; Förderquote nicht angegeben
Eigenanteil: Nicht erforderlich
Wahrscheinliche Antragstellende: Öffentliche Stellen, KMU / Start-ups, Unternehmen, Hochschulen & Forschung, Gemeinnützige Aus Quellkategorien oder Programmregeln; maßgeblich ist die Ausschreibung.
Fördergeber: National Institutes of Health
Referenz: PAR-28-009
Assistance Listing (USA): 93.473 Complementary and Integrative Health - Research Projects
Zuletzt geprüft: 15. November 2026

Offizielle Ausschreibung öffnen ↗

Die offiziellen Beschreibungen sind in der Sprache des Fördergebers (meist Englisch); Zusammenfassung und Eckdaten auf dieser Seite sind auf Deutsch.

Über diese Ausschreibung

The National Center for Complementary and Integrative Health (NCCIH) intends to publish a Notice of Funding Opportunity (NOFO) to support collaborative interdisciplinary research that advances foundational understanding of non-addictive natural products for chronic pain management through a holistic, system-oriented approach. This initiative aligns with the NIH Helping to End Addiction Long-term (HEAL) Initiative by promoting safe, non-addictive, and prevention-oriented strategies for pain relief.

Chronic pain affects tens of millions of adults in the United States, contributing to disability, diminished quality of life, and significant healthcare costs. Despite widespread public use of natural products, such as botanicals, dietary supplements, and other naturally derived compounds for pain relief, scientific evidence has not kept pace with demand. Existing research often focuses on single molecular targets or isolated pathways, which fail to capture the complex, multisystem actions of these products.

Vollständigen Text lesen

The scope of natural products under this NOFO includes those commonly used by the public as well as those with emerging usage or therapeutic potential. Research is expected to take a holistic approach that examines how these products influence pain through coordinated biological pathways across the multiple organ systems, such as digestive, immune, vascular, musculoskeletal, lymphatic, metabolic/adipose tissues, and nervous system. Studies should also explore dose optimization based on the principle of hormesis, where low doses may elicit beneficial or adaptive effects while higher doses could be ineffective or harmful. In addition, investigators are encouraged to identify optimal intervention timing that aligns with the dynamic phases of pain and inflammation, thereby maximizing therapeutic outcomes and supporting physiological recovery.

This program emphasizes rigorous mechanistic studies that generate foundational insights to inform future translational research and guide the development of safe, evidence-based, non-addictive strategies for pain management.

Wer kann sich bewerben?

County governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
For profit organizations other than small businesses
Private institutions of higher education
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
State governments
Special district governments
Native American tribal organizations (other than Federally recognized tribal governments)
Public housing authorities/Indian housing authorities

Antragstellerkategorien sind nur ein Ausgangspunkt. Über die Antragsberechtigung entscheidet die offizielle Ausschreibung.

Themen

Health

So bewerben Sie sich

Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

Kontakt

Division of Extramural Research (DER) Program Officer · NCCIHDERFunding@nih.gov · Please contact via e-mail.

Offizielle Quellen

Offizielle Ausschreibungsseite

Die Angaben auf dieser Seite stammen aus der offiziellen Quelle und wurden zuletzt am 15. November 2026 geprüft. Maßgeblich sind immer die Unterlagen des Fördergebers einschließlich späterer Änderungen.