National Institutes of Health · United States

Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

Open

National Institutes of Health expects to make 10 awards of up to $1.75 million each, from a total budget of $22 million. Applications close on 25 Sep 2028. Eligible applicant types include private institutions of higher education and public and State controlled institutions of higher education.

Deadline: 25 Sep 2028 (in 680 days)
Grant amount: Up to $1.75 million per project
Total budget: $22 million
Funding rate: No mandatory cost sharing stated; funding percentage not stated
Total budget: $22 million
Expected awards: 10
Cost sharing: Not required
Likely applicant types: Universities & research From source categories or programme rules; the call decides.
Funder: National Institutes of Health
Reference: RFA-ES-27-004
Assistance listing: 93.143 NIEHS Superfund Hazardous Substances_Basic Research and Education
Last checked: 13 Nov 2026

Open the official call ↗ Add deadline to calendar

About this call

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Who can apply

Private institutions of higher education
Public and State controlled institutions of higher education

Based on 42 USC 9660(a)(3) eligible applicants are limited to accredited institutes of higher education. Eligible applicants are permitted under the law, and encouraged by NIEHS, to subcontract as appropriate with other organizations as necessary to conduct portions of the research. Examples of other organizations may include generators of hazardous wastes; persons involved in the detection, assessment, evaluation, and treatment of hazardous substances; owners and operators of facilities at which hazardous substances are located; and/or State and local governments. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Applicant categories are a starting point. The official call decides eligibility.

Topics

Health

How to apply

Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

Contact

National Institutes of Health · 301-402-2541

Where these facts come from

Fact	Value	How we know	Taken from the source
Deadline	25 September 2028	official data field	15 Nov 2026
Amount per applicant	Up to $1.75 million	official data field	15 Nov 2026
Total budget	$22 million	official data field	15 Nov 2026
Funding rate	No mandatory cost sharing stated; funding percentage not stated	read from the official text	15 Nov 2026
Who can apply	Private institutions of higher education; Public and State controlled institutions of higher education	official data field	15 Nov 2026
Where to apply	Unknown — not stated in the source we hold	unknown	—

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.