Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years… (P50 Clinical Trial Required)
Full title in the source: Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)
Open
National Institutes of Health expects to make 10 awards, from a total budget of $1.4 million. Applications close on 25 Sep 2029. Eligible applicant types include county governments, independent school districts, for profit organizations other than small businesses and 12 more.
Deadline
25 Sep 2029 (in 1045 days)
Grant amount
≈ $140,000 per award (estimate: total ÷ 10 awards)
Total budget
$1.4 million
Funding rate
No mandatory cost sharing stated; funding percentage not stated
Total budget
$1.4 million
Expected awards
10
Cost sharing
Not required
Likely applicant types
Public bodies, SMEs / start-ups, Companies, Universities & research, Non-profits From source categories or programme rules; the call decides.
Funder
National Institutes of Health
Reference
PAR-28-022
Assistance listing
93.121 Oral Diseases and Disorders Research; 93.395 Cancer Treatment Research
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPOREs). Based on the proposed research, applications may be jointly funded with the National Institute of Dental and Craniofacial Research (NIDCR). This is a re-issuance of PAR-23-284 . The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. The research supported through this program must be translational and be based on human biology research using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must reach a translational human endpoint within the project period of the grant.
Who can apply
County governments
Independent school districts
For profit organizations other than small businesses
State governments
Private institutions of higher education
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Special district governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Applicant categories are a starting point. The official call decides eligibility.
Topics
Health
How to apply
Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.
From the call text
Who can apply
Not stated in the call text we hold — check the official page
Company stage
Not stated in the call text we hold — check the official page
Single applicant or consortium
Not stated in the call text we hold — check the official page
Where applicants must be based
Not stated in the call text we hold — check the official page
Where to apply
Not stated in the call text we hold — check the official page
No mandatory cost sharing stated; funding percentage not stated
read from the official text
15 Nov 2026
Who can apply
County governments; Independent school districts; For profit organizations other than small businesses; State governments; Private institutions of higher education; Public and State controlled institutions of higher…
Facts on this page come from the funder’s official data, taken on 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.
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