Centers for Disease Control and Prevention - ERA · United States

Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

Open

Centers for Disease Control and Prevention - ERA expects to make 36 awards of up to $365,000 each, from a total budget of $18 million. Applications close on 8 Dec 2026. Eligible applicant types include nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, independent school districts, city or township governments and 12 more.

Deadline: 8 Dec 2026 (in 23 days)
Grant amount: Up to $365,000 per project
Total budget: $18 million
Funding rate: No mandatory cost sharing stated; funding percentage not stated
Total budget: $18 million
Expected awards: 36
Cost sharing: Not required
Likely applicant types: Non-profits, Universities & research, Public bodies, SMEs / start-ups, Companies, Individuals From source categories or programme rules; the call decides.
Funder: Centers for Disease Control and Prevention - ERA
Reference: RFA-OH-26-015
Assistance listing: 93.262 Occupational Safety and Health Program
Last checked: 13 Nov 2026

Open the official call ↗ Add deadline to calendar

About this call

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

Who can apply

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
City or township governments
Special district governments
For profit organizations other than small businesses
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Public housing authorities/Indian housing authorities
Private institutions of higher education
Small businesses
County governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Public and State controlled institutions of higher education

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Applicant categories are a starting point. The official call decides eligibility.

Topics

Health

Timing

December 8, 2026; October 26, 2027. All applications must be submitted no later than 11:59 pm local time of the applicant organization.

How to apply

Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
Register with Grants.gov and set up a Workspace for this opportunity, with the right roles for your organisation.
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

Contact

Centers for Disease Control and Prevention - ERA · jcy5@cdc.gov · 404-498-2015

Where these facts come from

Fact	Value	How we know	Taken from the source
Deadline	8 December 2026	official data field	15 Nov 2026
Amount per applicant	Up to $365,000	official data field	15 Nov 2026
Total budget	$18 million	official data field	15 Nov 2026
Funding rate	No mandatory cost sharing stated; funding percentage not stated	read from the official text	15 Nov 2026
Who can apply	Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; City or township governments; Special district governments; For profit organizations other…	official data field	15 Nov 2026
Where to apply	Unknown — not stated in the source we hold	unknown	—

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.