Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
Open
National Institutes of Health expects to make awards of $50,000 – $400,000 each. Applications close on 1 Jul 2028. Eligible applicant types include for profit organizations other than small businesses, native American tribal organizations (other than Federally recognized tribal governments), nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education and 12 more.
Deadline
1 Jul 2028 (in 594 days)
Grant amount
$50,000 – $400,000 per project
Funding rate
No mandatory cost sharing stated; funding percentage not stated
Cost sharing
Not required
Likely applicant types
SMEs / start-ups, Companies, Public bodies, Non-profits, Universities & research From source categories or programme rules; the call decides.
Funder
National Institutes of Health
Reference
PAR-27-021
Assistance listing
93.310 Trans-NIH Research Support; 93.351 Research Infrastructure Programs; 93.855 Allergy and Infectious Diseases Research; 93.866 Aging Research
This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.
Who can apply
For profit organizations other than small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public housing authorities/Indian housing authorities
Special district governments
City or township governments
County governments
Small businesses
Native American tribal governments (Federally recognized)
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
State governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Applicant categories are a starting point. The official call decides eligibility.
Topics
Health
How to apply
Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.
From the call text
Who can apply
Not stated in the call text we hold — check the official page
Company stage
Not stated in the call text we hold — check the official page
Single applicant or consortium
Not stated in the call text we hold — check the official page
Where applicants must be based
Not stated in the call text we hold — check the official page
Where to apply
Not stated in the call text we hold — check the official page
No mandatory cost sharing stated; funding percentage not stated
read from the official text
15 Nov 2026
Who can apply
For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than…
Facts on this page come from the funder’s official data, taken on 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.
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