National Institutes of Health · United States

Feasibility Studies to Inform the Design of Future Clinical Trials

Forecast — expected to open 24 Nov 2026

This is a forecast: the funder has announced the opportunity but it is not open yet; posting is expected around 24 Nov 2026 and the estimated deadline is 16 Feb 2027. Eligible applicant types include nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, native American tribal governments (Federally recognized), native American tribal organizations (other than Federally recognized tribal governments) and 12 more.

Deadline: Estimated 16 Feb 2027 (not yet confirmed)
Opens: 24 Nov 2026
Grant amount: Not stated — see the official call
Funding rate: No mandatory cost sharing stated; funding percentage not stated
Cost sharing: Not required
Likely applicant types: Non-profits, Universities & research, Public bodies, SMEs / start-ups, Companies From source categories or programme rules; the call decides.
Funder: National Institutes of Health
Reference: PAR-28-011
Assistance listing: 93.213 Research and Training in Complementary and Integrative Health
Last checked: 15 Nov 2026

Open the official call ↗

About this call

The National Institutes of Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose feasibility studies that could inform the design and conduct of subsequent definitive clinical trials (e.g., efficacy, effectiveness, pragmatic, dissemination and implementation, phase/stage II or later trials). Applications to this NOFO should demonstrate that the proposed feasibility research is scientifically necessary to design or plan the subsequent definitive clinical trial. Studies may utilize mixed methods and feasibility clinical trials to assess feasibility of recruitment, randomization, retention, intervention delivery, data collection, adherence, acceptability, and/or develop or adapt intervention components or protocols. The proposed feasibility research should enhance the rigor and reproducibility of the future trial methods. The subsequent definitive clinical trial should have the potential to make a significant impact on public health.

Read the full text

Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise in clinical trial planning, design, implementation, intervention development, and/or stakeholder engagement are encouraged to begin to consider applying for this new NOFO.

Who can apply

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
Small businesses
Independent school districts
Public and State controlled institutions of higher education
State governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Special district governments
County governments

Applicant categories are a starting point. The official call decides eligibility.

Topics

Health

How to apply

Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

Contact

NCCIH Division of Extramural Research Program Officer · NCCIHDERFunding@nih.gov · Please contact via e-mail

Where these facts come from

Fact	Value	How we know	Taken from the source
Deadline	16 February 2027	official data field	15 Nov 2026
Amount per applicant	Unknown — not stated in the source we hold	unknown	—
Total budget	Unknown — not stated in the source we hold	unknown	—
Funding rate	No mandatory cost sharing stated; funding percentage not stated	read from the official text	15 Nov 2026
Who can apply	Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally…	official data field	15 Nov 2026
Where to apply	Unknown — not stated in the source we hold	unknown	—

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 15 Nov 2026. The funder's own documents, including later amendments, always take precedence.