U.S. National Science Foundation · United States

Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)

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U.S. National Science Foundation expects to make 50 awards, from a total budget of $100 million. Applications close on 3 Nov 2027. Eligible applicant types include others (see text field entitled "Additional Information on Eligibility" for clarification).

Deadline: 3 Nov 2027 (in 353 days)
Grant amount: ≈ $2 million per award (estimate: total ÷ 50 awards)
Total budget: $100 million
Funding rate: No mandatory cost sharing stated; funding percentage not stated
Total budget: $100 million
Expected awards: 50
Cost sharing: Not required
Funder: U.S. National Science Foundation
Reference: 26-512
Assistance listing: 47.041 Engineering; 47.049 Mathematical and Physical Sciences; 47.050 Geosciences; 47.074 Biological Sciences; 47.084 NSF Technology, Innovation, and Partnerships
Last checked: 13 Nov 2026

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About this call

This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis.

The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis.

Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms , the NSF Integrated Data Systems and Services program , the NSF-led National AI Research Resource , the Genesis Mission platform , or other national infrastructure.

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NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets.

Expanding Participation in STEM, NSF Priorities, and Gold Standard Science:

NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission . Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.

Who can apply

Others (see text field entitled "Additional Information on Eligibility" for clarification)

*Who May Submit Proposals: Proposals may only be submitted by the following:

-For-profit organizations: U.S.-based commercial organizations, including small businesses, with strong capabilities in scientific or engineering research or education and a passion for innovation.

-Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities.

-Other Federal Agencies and Federally Funded Research and Development Centers (FFRDCs): Prospective proposers from other Federal Agencies and FFRDCs, including NSF sponsored FFRDCs, must follow the guidance in PAPPG Chapter I.E.2 regarding limitations on eligibility.

-State and Local Governments

-Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.

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-Tribal Nations: An American Indian or Alaska Native…

Applicant categories are a starting point. The official call decides eligibility.

Topics

Science and Technology and other Research and Development

How to apply

Apply through the funder’s official page (link below); it states the procedure, documents and deadline.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

Contact

U.S. National Science Foundation · grantsgovsupport@nsf.gov · 703-292-4203

Where these facts come from

Fact	Value	How we know	Taken from the source
Deadline	3 November 2027	official data field	15 Nov 2026
Amount per applicant	Unknown — not stated in the source we hold	unknown	—
Total budget	$100 million	official data field	15 Nov 2026
Funding rate	No mandatory cost sharing stated; funding percentage not stated	read from the official text	15 Nov 2026
Who can apply	Others (see text field entitled "Additional Information on Eligibility" for clarification)	official data field	15 Nov 2026
Where to apply	Unknown — not stated in the source we hold	unknown	—

Official sources

Official call page · Funder's programme page

Facts on this page come from the funder’s official data, taken on 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.