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National Institutes of Health · United States

Investigator-Focused Award (Parent R35)

Forecast — expected to open 27 May 2027

This is a forecast: the funder has announced the opportunity but it is not open yet; posting is expected around 27 May 2027 and the estimated deadline is 4 Oct 2027. Eligible applicant types include special district governments, independent school districts, nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education and 12 more.

About this call

The National Institutes of Health intends to publish a Parent R35 "Investigator-Focused Award" Notice of Funding Opportunity (NOFO) to fund research programs for investigators at all career stages, including Early Stage Investigators (ESIs). The Parent R35 Investigator-Focused Award is intended to provide support for an investigator's program of research within the mission of the awarding Institute or Center (IC) rather than support for a pre-defined project with specific aims.

The R35 is typically expected to be an investigator's primary (or only) source of research funding from the awarding IC.

An R35 award gives investigators funding stability and scientific freedom. With R35 support, researchers can pursue ambitious and innovative studies without the pressure of constantly seeking new funding streams. Key benefits include:

• Providing flexibility to follow the science as it evolves within the awarding IC's mission.

Who can apply

• Special district governments
• Independent school districts
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• For profit organizations other than small businesses
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Public housing authorities/Indian housing authorities
• City or township governments
• Native American tribal governments (Federally recognized)
• Public and State controlled institutions of higher education
• Private institutions of higher education
• Small businesses
• State governments
• County governments
• Native American tribal organizations (other than Federally recognized tribal governments)

Applicant categories are a starting point. The official call decides eligibility.

Topics

Health

How to apply

1. Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
2. Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
3. For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
4. Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
5. Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply

Not stated in the call text we hold — check the official page

Company stage

Not stated in the call text we hold — check the official page

Single applicant or consortium

Not stated in the call text we hold — check the official page

Where applicants must be based

Not stated in the call text we hold — check the official page

Where to apply

Not stated in the call text we hold — check the official page

Contact

Office of Extramural Research · ParentR35@mail.nih.gov · Please contact via e-mail

Where these facts come from

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 15 Nov 2026. The funder's own documents, including later amendments, always take precedence.

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