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U.S. National Science Foundation · United States

Core Research in Biological Sciences (BIO Core)

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U.S. National Science Foundation expects to make 300 awards of $500,000 each, from a total budget of $280 million. Eligible applicant types include others (see text field entitled "Additional Information on Eligibility" for clarification).

Deadline
Not published yet — check the official call
Grant amount
$500,000 per project
Total budget
$280 million
Funding rate
No mandatory cost sharing stated; funding percentage not stated
Total budget
$280 million
Expected awards
300
Cost sharing
Not required
Funder
U.S. National Science Foundation
Reference
26-517
Assistance listing
47.074 Biological Sciences
Last checked
13 Nov 2026

Open the official call ↗

About this call

The U.S. National Science Foundation's Directorate for Biological Sciences (NSF BIO) Core Research in Biological Sciences (BIO Core) funding opportunity supports foundational and interdisciplinary research projects that expand knowledge of biology at any level of organization, from the molecular to the biome scale. We accept proposals that cover scientific topics associated with legacy programs historically supported by NSF BIO and proposals that explore new areas of biological sciences.

BIO Core funds single- and multi-investigator awards. The portfolio of awards is anticipated to include a range of budgets and durations, including exploratory projects of smaller scope and long-horizon projects that benefit from longer-term commitment. BIO Core awards are subject to the availability of funds.

Who can apply

*Who May Submit Proposals: Proposals may only be submitted by the following:

-Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities.

-Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.

Read the full text

-Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131.

Applicant categories are a starting point. The official call decides eligibility.

Topics

Science and Technology and other Research and Development

Timing

Proposals accepted anytime

How to apply

  1. Apply through the funder’s official page (link below); it states the procedure, documents and deadline.

From the call text

Who can apply
Not stated in the call text we hold — check the official page
Company stage
Not stated in the call text we hold — check the official page
Single applicant or consortium
Not stated in the call text we hold — check the official page
Where applicants must be based
*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members.
Where to apply
Not stated in the call text we hold — check the official page

Contact

U.S. National Science Foundation · grantsgovsupport@nsf.gov · 703-292-4203

Official sources

Official call page · Funder's programme page

Facts on this page come from the official source and were last checked 13 Nov 2026. The funder's own documents, including later amendments, always take precedence.

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