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National Institutes of Health · United States

Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences

Forecast — expected to open 23 Apr 2027

This is a forecast: the funder has announced the opportunity but it is not open yet; posting is expected around 23 Apr 2027 and the estimated deadline is 25 May 2027. Eligible applicant types include independent school districts, state governments, native American tribal governments (Federally recognized) and 12 more.

About this call

The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with other National Institutes of Health (NIH) Institutes, Centers, and Offices, intends to support research projects that directly improve or evaluate biomedical and behavioral rigor, replicability, and reproducibility. Example projects include, but are not limited to:

• Assessing the scientific and behavioral impact of improving rigor, replicability, and reproducibility

• Developing decision-making frameworks to select candidate studies for replication with the highest potential for scientific value or novel insights

• Measuring replicability, reproducibility, robustness, and generalizability of important research findings to accelerate scientific innovation

Applications are not being solicited at this time. This notice is to allow applicants time to develop collaborations and responsive projects.

Who can apply

• Independent school districts
• State governments
• Native American tribal governments (Federally recognized)
• Special district governments
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Small businesses
• County governments
• Native American tribal organizations (other than Federally recognized tribal governments)
• Private institutions of higher education
• City or township governments
• For profit organizations other than small businesses
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Public and State controlled institutions of higher education
• Public housing authorities/Indian housing authorities

Applicant categories are a starting point. The official call decides eligibility.

Topics

Health

How to apply

1. Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
2. Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
3. For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
4. Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
5. Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply

Not stated in the call text we hold — check the official page

Company stage

Not stated in the call text we hold — check the official page

Single applicant or consortium

Not stated in the call text we hold — check the official page

Where applicants must be based

Not stated in the call text we hold — check the official page

Where to apply

Not stated in the call text we hold — check the official page

Contact

NINDS Office of Research Quality (ORQ) · RigorChampions@nih.gov · Please contact via e-mail.

Where these facts come from

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 15 Nov 2026. The funder's own documents, including later amendments, always take precedence.

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