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Horizon Europe · European Union

Microbiome for terrestrial livestock sustainability and health within a One Health approach

Opens 20 Apr 2027

The EU's Horizon Europe programme expects to make 2 awards of €5 million – €6 million each, from a total budget of €11.8 million. Applications close on 23 Sep 2027 (EU calls usually close at 17:00 Brussels time). Organisations in EU member states and Horizon Europe associated countries such as Türkiye can usually take part; the topic conditions control.

Deadline
23 Sep 2027 (in 312 days)
Opens
20 Apr 2027
Grant amount
€5 million – €6 million per project
Total budget
€11.8 million
Funding rate
100% of eligible costs Standard rule for this programme; the call can differ.
Total budget
€11.8 million
Expected awards
2
Type of action
HORIZON Research and Innovation Actions · HORIZON Lump Sum Grant
Likely applicant types
Companies, SMEs / start-ups, Non-profits, Universities & research, Public bodies From source categories or programme rules; the call decides.
Funder
Horizon Europe (HORIZON)
Reference
HORIZON-CL6-2027-02-FARM2FORK-03
Call
HORIZON-CL6-2027-02
Last checked
14 Nov 2026

Open the official call ↗ Add deadline to calendar

Expected outcome

Project results are expected to contribute to all the following expected outcomes:

• the research community, farmers, livestock industry e.g. breeders, service providers, policymakers understand better the role of the microbiome on livestock health and production and the interaction with environment and human health within a One Health approach;

• researchers' communities and innovators in the livestock sector have access to a platform of tools for data sharing, knowledge exchange, capacity building and standardization in microbiome research and its applications through synergies with other platforms in a One Health context;

• targeted strategies and guidelines are available to farmers, service providers and livestock industry to contribute to improving livestock health, while reducing antimicrobial use and environmental impact, and securing animal welfare.

Scope

Microbiome research offers transformative potential for livestock management within the One Health (OH) framework, which emphasises the interconnected health of animals, humans, and the environment. In livestock, microbiome innovation can address pressing issues such as antimicrobial resistance (AMR) and zoonotic disease transmission. However, gaps persist in understanding the role of variability within host-microbiome interactions, in developing sustainable farming practices, and assessing these interventions in real-world farming settings. Advancing microbiome research can enhance animal health and productivity, improve ecosystems, while reducing environmental and climate impacts. By focusing on microbiome-based solutions, the objective is to support sustainable livestock systems that align with OH principles, necessitating cross-disciplinary collaboration to ensure comprehensive health benefits.

Read the full text

Proposals should address all of the following activities:

• investigate the microbiome of terrestrial livestock, their influence on animal health, taking into account the holobiont/hologenome perspectives, and the interactions with the environment (soil, plant, water, air) and human health;

• develop integrated data monitoring systems that track microbiome related health indicators across livestock, plant, and human health sectors, and help in risk assessment models for zoonotic disease and/or AMR emergence and transmission;

• assess how microbiome-based solutions for animal health affect, and are affected by, soil and plant health, and the use of chemical fertilisers and pesticides;

• design holistic health models that incorporate microbiome research to enhance the robustness of animals as well as animal health and welfare, and overall productivity, taking into account soil and plant health, and to assess potential synergies and trade-offs between these objectives;

• design microbiome related intervention strategies to prevent outbreaks and cross-species transmission in animal populations and reduce the risk of zoonosis, thereby contributing to reduced antimicrobial usage while enhancing resilience, animal welfare, and minimizing environmental impact;

• develop, or contribute to, platforms to collaboratively assess and optimise the efficacy and implementation of microbiome-based tools, products and services in the livestock sector through synergies with other platforms within a One Health context;

• enhance collaboration among veterinarians, microbiologists, geneticists, animal and plant biologists, epidemiologists, and ecologists and other experts to work towards a One Health approach.

Projects selected under this topic should interact between themselves and build on/interact with recent or on-going EU funded projects and initiatives, including those funded under the topic HORIZON-CL6-2026-02-FARM2FORK-11: Integrating a holistic perspective in microbiome research for resilient, competitive and sustainable food systems, as well as with relevant…

Who can apply

Consortium of at least 3 independent legal entities from 3 different EU Member States or associated countries, at least one in a Member State (Horizon Europe standard rule).

Applicant categories are a starting point. The official call decides eligibility.

Topics

Animal health Biochemistry and molecular biology Cell biology, Microbiology Genomics, comparative genomics, functional genomics Animal-plant-soil interactions Cross-disciplinary collaboration Microbiome One Health Terrestrial livestock

Timing

Single-stage call. Next deadline 2027-09-23. The portal states the exact cut-off time (EU calls usually close at 17:00 Brussels time).

How to apply

  1. Read the full topic on the Funding & Tenders Portal: expected outcome, scope, type of action and the topic conditions, including any country restrictions.
  2. Register each participating organisation in the Funding & Tenders Portal to get a PIC.
  3. Consortium of at least 3 independent legal entities from 3 different EU Member States or associated countries (Horizon Europe standard rule; Türkiye is associated). Confirm in the topic conditions.
  4. Prepare Part A (administrative forms and budget, completed in the portal) and Part B (the technical description on the official template for this type of action).
  5. Submit in the portal before the cut-off time on the deadline day. Late submissions are not accepted.

From the call text

Who can apply
Not stated in the call text we hold — check the official page
Company stage
Not stated in the call text we hold — check the official page
Single applicant or consortium
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.
Where applicants must be based
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.
Where to apply
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.

Read the EU application guide

Where these facts come from

FactValueHow we knowTaken from the source
Deadline23 September 2027
“Single-stage call. Next deadline 2027-09-23. The portal states the exact cut-off time (EU calls usually close at 17:00 Brussels time).”
official data field15 Nov 2026
Amount per applicantUnknown — not stated in the source we holdunknown—
Total budget€11.8 millionofficial data field15 Nov 2026
Funding rate100% of eligible costsprogramme standard rule15 Nov 2026
Who can applyConsortium of at least 3 independent legal entities from 3 different EU Member States or associated countries, at least one in a Member State (Horizon Europe standard rule).programme standard rule15 Nov 2026
Where to applyRead the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.read from the official text15 Nov 2026

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 14 Nov 2026. The funder's own documents, including later amendments, always take precedence.

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