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Horizon Europe · European Union

Towards the next generation of frontier Artificial Intelligence models for healthcare

Opens 3 Jun 2027

The EU's Horizon Europe programme expects to make 1 award of €2.9 million, from a total budget of €2.9 million. Applications close on 16 Sep 2027 (EU calls usually close at 17:00 Brussels time). Organisations in EU member states and Horizon Europe associated countries such as Türkiye can usually take part; the topic conditions control.

Expected outcome

This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes:

• Researchers and innovators benefit from an improved understanding of how to develop and use the next generation of frontier Artificial Intelligence (AI) models for healthcare, including how to leverage AI Factories and how to combine and expand the capabilities of existing foundation models towards inclusive and personalised medicine.

• Researchers and innovators benefit from an improved understanding of how to leverage highly heterogeneous and multimodal health data spanning a range of anatomical scales (i.e. the micro to the macro level).

Scope

The AI Continent Action Plan [1] identifies the health sector, encompassing life sciences, medical devices and healthcare delivery, as one of the key strategic sectors. The action will contribute to making European life sciences [2] and healthcare more impactful and productive by fostering the full integration of advanced AI in the health sector and biomedical research, along the objectives of the AI in Science strategy [3] and Apply AI strategy [4] .

Healthcare typically involves the combining of multimodal data, ranging from electronic health records through imaging and laboratory to molecular and omics data. This information combination is performed by specialists and is often challenging towards optimised patient care. In Europe, the growing amount of accessible multimodal health data, including via the forthcoming European Health Data Space (EHDS) [5] , combined with the increasing availability of high-performance computing facilities (e.g. AI Factories), presents a unique opportunity to develop the next generation of frontier AI models for healthcare. This action anticipates and operationalises the use of such federated infrastructures for research and innovation. Moreover, regulations such as the EHDS regulation and AI Act [6] steer the direction into building an ecosystem fostering ethical and safe innovation on AI in healthcare.

Who can apply

A single organisation from an EU Member State or associated country can apply (Horizon Europe standard rule). Country restriction: participation is limited to legal entities established in Member States and Associated Countries.

Applicant categories are a starting point. The official call decides eligibility.

Topics

Artificial Intelligence & Decision support Artificial intelligence, intelligent systems, multi agent systems Basic medicine Big data Clinical medicine Data protection and privacy Health sciences Machine learning, statistical data processing and applications using signal processing (e.g. speech, image, video) Medical engineering, biomedical engineering and technology Personalised medicine Artificial intelligence Foundation model Frontier model Heterogeneous data Multimodal data Trustworthy artificial intelligence

Timing

Single-stage call. Next deadline 2027-09-16. The portal states the exact cut-off time (EU calls usually close at 17:00 Brussels time).

How to apply

1. Read the full topic on the Funding & Tenders Portal: expected outcome, scope, type of action and the topic conditions, including any country restrictions.
2. Register each participating organisation in the Funding & Tenders Portal to get a PIC.
3. This topic is for a single applicant: no consortium is needed (check the topic conditions for who qualifies).
4. Prepare Part A (administrative forms and budget, completed in the portal) and Part B (the technical description on the official template for this type of action).
5. Submit in the portal before the cut-off time on the deadline day. Late submissions are not accepted.

From the call text

Who can apply

Not stated in the call text we hold — check the official page

Company stage

Not stated in the call text we hold — check the official page

Single applicant or consortium

Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.

Where applicants must be based

Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.

Where to apply

Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.

Read the EU application guide

Where these facts come from

Official sources

Official call page

Facts on this page come from the funder’s official data, taken on 14 Nov 2026. The funder's own documents, including later amendments, always take precedence.

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