← Tüm fırsatlar

National Institutes of Health · ABD

Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)

Açık

Başvurular 2 Temmuz 2027 tarihinde kapanıyor. Uygun başvuru sahibi türleri (kaynakta): City or township governments, Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education ve 12 diğer.

Resmi açıklamalar fon sağlayıcının dilindedir (çoğunlukla İngilizce); bu sayfadaki özet ve temel bilgiler Türkçedir.

Çağrı hakkında

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur therapeutic development for a variety of rare diseases by advancing projects to the point where they would attract subsequent investment supporting full Investigational New Drug (IND) application development or progression to clinical trials in the case of repurposing or repositioning.

Kimler başvurabilir

• City or township governments
• Small businesses
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Private institutions of higher education
• State governments
• County governments
• Special district governments
• For profit organizations other than small businesses
• Public and State controlled institutions of higher education
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Native American tribal governments (Federally recognized)
• Independent school districts
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Public housing authorities/Indian housing authorities
• Native American tribal organizations (other than Federally recognized tribal governments)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Başvuru sahibi kategorileri yalnızca bir başlangıç noktasıdır. Uygunluğa resmi çağrı karar verir.

Konular

Health

Nasıl başvurulur

1. Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
2. Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
3. For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
4. Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
5. Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply

Not stated in the call text we hold — check the official page

Company stage

Not stated in the call text we hold — check the official page

Single applicant or consortium

Not stated in the call text we hold — check the official page

Where applicants must be based

Not stated in the call text we hold — check the official page

Where to apply

Not stated in the call text we hold — check the official page

İletişim

National Institutes of Health · grantsinfo@nih.gov · 301-402-2541

Resmi kaynaklar

Resmi çağrı sayfası · Fon sağlayıcının program sayfası

Bu sayfadaki bilgiler resmi kaynaktan alınmıştır ve en son 13 Kasım 2026 tarihinde kontrol edilmiştir. Sonraki değişiklikler dahil, fon sağlayıcının kendi belgeleri her zaman önceliklidir.

National Institutes of Health: diğer çağrılar