National Institutes of Health · ABD

A Holistic Approach to Study Non-Addictive Natural Products for Pain Management

Ön duyuru — 2 Şubat 2027 tarihinde açılması bekleniyor

Bu bir ön duyurudur: fon sağlayıcı fırsatı duyurdu ancak henüz başvuruya açık değil; yayınlanması yaklaşık 2 Şubat 2027 tarihinde bekleniyor, tahmini son tarih 25 Mayıs 2027. Uygun başvuru sahibi türleri (kaynakta): County governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), For profit organizations other than small businesses ve 12 diğer.

Son başvuru: Tahmini 25 Mayıs 2027 (henüz kesin değil)
Açılış: 2 Şubat 2027
Hibe tutarı: Belirtilmemiş — resmi çağrıya bakın
Destek oranı: Zorunlu eş finansman belirtilmemiş; destek oranı belirtilmemiş
Eş finansman: Gerekli değil
Olası başvuru sahipleri: Kamu kurumları, KOBİ’ler / girişimler, Şirketler, Üniversiteler ve araştırma, Kâr amacı gütmeyenler Kaynak kategorilerinden veya program kurallarından; uygunluğa çağrı karar verir.
Fon sağlayıcı: National Institutes of Health
Referans: PAR-28-009
Destek listesi (ABD): 93.473 Complementary and Integrative Health - Research Projects
Son kontrol: 15 Kasım 2026

Resmi çağrıyı aç ↗

Resmi açıklamalar fon sağlayıcının dilindedir (çoğunlukla İngilizce); bu sayfadaki özet ve temel bilgiler Türkçedir.

Çağrı hakkında

The National Center for Complementary and Integrative Health (NCCIH) intends to publish a Notice of Funding Opportunity (NOFO) to support collaborative interdisciplinary research that advances foundational understanding of non-addictive natural products for chronic pain management through a holistic, system-oriented approach. This initiative aligns with the NIH Helping to End Addiction Long-term (HEAL) Initiative by promoting safe, non-addictive, and prevention-oriented strategies for pain relief.

Chronic pain affects tens of millions of adults in the United States, contributing to disability, diminished quality of life, and significant healthcare costs. Despite widespread public use of natural products, such as botanicals, dietary supplements, and other naturally derived compounds for pain relief, scientific evidence has not kept pace with demand. Existing research often focuses on single molecular targets or isolated pathways, which fail to capture the complex, multisystem actions of these products.

Tam metni oku

The scope of natural products under this NOFO includes those commonly used by the public as well as those with emerging usage or therapeutic potential. Research is expected to take a holistic approach that examines how these products influence pain through coordinated biological pathways across the multiple organ systems, such as digestive, immune, vascular, musculoskeletal, lymphatic, metabolic/adipose tissues, and nervous system. Studies should also explore dose optimization based on the principle of hormesis, where low doses may elicit beneficial or adaptive effects while higher doses could be ineffective or harmful. In addition, investigators are encouraged to identify optimal intervention timing that aligns with the dynamic phases of pain and inflammation, thereby maximizing therapeutic outcomes and supporting physiological recovery.

This program emphasizes rigorous mechanistic studies that generate foundational insights to inform future translational research and guide the development of safe, evidence-based, non-addictive strategies for pain management.

Kimler başvurabilir

County governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
For profit organizations other than small businesses
Private institutions of higher education
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
State governments
Special district governments
Native American tribal organizations (other than Federally recognized tribal governments)
Public housing authorities/Indian housing authorities

Başvuru sahibi kategorileri yalnızca bir başlangıç noktasıdır. Uygunluğa resmi çağrı karar verir.

Konular

Health

Nasıl başvurulur

Read the full notice of funding opportunity (NOFO) linked from the official page: eligibility, cost sharing and evaluation criteria.
Make sure your organisation has an active SAM.gov registration and Unique Entity ID (UEI); registration can take several weeks.
For NIH: the organisation and the principal investigator also need eRA Commons accounts; applications are usually submitted through Grants.gov (for example with ASSIST).
Prepare the required forms, narrative, budget and attachments exactly as the NOFO specifies.
Submit before the deadline and keep the tracking number. Check for amendments before you submit.

From the call text

Who can apply: Not stated in the call text we hold — check the official page
Company stage: Not stated in the call text we hold — check the official page
Single applicant or consortium: Not stated in the call text we hold — check the official page
Where applicants must be based: Not stated in the call text we hold — check the official page
Where to apply: Not stated in the call text we hold — check the official page

İletişim

Division of Extramural Research (DER) Program Officer · NCCIHDERFunding@nih.gov · Please contact via e-mail.

Resmi kaynaklar

Resmi çağrı sayfası

Bu sayfadaki bilgiler resmi kaynaktan alınmıştır ve en son 15 Kasım 2026 tarihinde kontrol edilmiştir. Sonraki değişiklikler dahil, fon sağlayıcının kendi belgeleri her zaman önceliklidir.