Neutral-Atom Platform Technologies
This action aims to establish European leadership in neutral-atom quantum simulation and digital quantum computing by delivering: • Fully programmable industry-ready quan…
Horizon Europe · Europäische Union
Full title in the source: Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change
Offen
Das EU-Programm Horizon Europe plant 4 Förderungen mit 10 Mio. € – 11 Mio. € pro Projekt bei einem Gesamtbudget von 45 Mio. €. Die Einreichungsfrist endet am 17. Februar 2027 (EU-Ausschreibungen enden meist um 17:00 Uhr Brüsseler Zeit). Organisationen aus EU-Mitgliedstaaten und assoziierten Ländern wie der Türkei können in der Regel teilnehmen; maßgeblich sind die Bedingungen des Topics.
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This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Living and working in a health-promoting environment”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to most of the following expected outcomes:
• Researchers, policymakers, healthcare practitioners and the public have a more comprehensive understanding of the human exposome and the interactions between climatic, environmental and socio-behavioural factors, supported by FAIR [1] data linking these exposures to disease and health outcomes.
• Researchers, governments, policymakers, social care services and healthcare practitioners have improved knowledge on the links between the climatic, social, lifestyle and environmental factors of the exposome and global health burden, supporting their efforts to adopt the exposome approach to identify and address relevant health impacts.
• The public has access to the latest information on the influence of global environmental exposures on health, enabling the adoption of health-promoting, climate-resilient and nature-positive behaviours.
The exposome is the totality of exposures (and their interactions) experienced by an individual throughout their lifetime, including chemical, physical, biological, nutritional and psychosocial factors, from conception onwards. Many of these factors originate in the environment, including climate-related exposures such as extreme heat, heightened air pollution or drought. Climate change may amplify or interact synergistically with other better-established exposures, dynamically altering the human exposome and its health implications. Despite this, climate factors remain underrepresented in large-scale human exposome studies.
Research activities under this topic should strengthen the use of the exposome approach to study global exposures and generate evidence on their health implications. Proposals should focus on integrating climate-related factors into exposome research and understanding how the exposome changes in response to direct and indirect climate exposures. Moreover, research activities should be multiscale and multidisciplinary and account for the complexity and multifactorial nature of health determinants and the most pressing unmet medical needs in relation to environmental degradation and disrupted ecosystems. Proposals should include climate-relevant social determinants of health as part of their proposed activities.
More specifically, research actions under this topic should include all the following activities:
• Incorporate multiple climate exposures into exposomics studies and provide insights on their influence on disease burden, through interactions with other exposome factors.
• Predict, identify and monitor changes in the exposome (including environmental, social and occupational exposures) resulting from climate-related pressures and study their health implications to identify emerging health risks and potential benefits of climate change.
• Advance data generation, analysis, integration and interpretation in human exposomics, developing methodologies and integrating novel approaches (e.g. AI technologies and machine learning) for advanced data analytics, including for Real-World Data (RWD) [2] .
In addition, research actions should include several of the following targeted activities:
• Establish and investigate the biological pathways and mechanisms by which the exposome drives health impacts, jointly considering climate-related and other exposures. Build upon (when relevant) and study existing and/or newly generated longitudinal cohorts that combine individual exposome data with the corresponding medical, omics and biological data.
• Identify exposome-relevant indicators and biomarkers for exposome-related health risks and potential benefits using comprehensive exposome studies that combine climate, environmental, behavioural and social exposures. Account for disparities in individual trajectories and exposure patterns where relevant.
• Report on health-relevant exposome findings using, where possible, standardised…
Consortium of at least 3 independent legal entities from 3 different EU Member States or associated countries, at least one in a Member State (Horizon Europe standard rule).
Antragstellerkategorien sind nur ein Ausgangspunkt. Über die Antragsberechtigung entscheidet die offizielle Ausschreibung.
Cohort studies Disease determinants Environmental health Environmental risk measurement Environmental stressors Epidemiology Health determinants Health inequalities Health outcomes Health promotion Public and environmental health Public health Public health and epidemiology Risk assessment Risk factors Biodiversity Climate Exposome Health Pollution
Single-stage call. Next deadline 2027-02-17. The portal states the exact cut-off time (EU calls usually close at 17:00 Brussels time).
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Offizielle Ausschreibungsseite
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