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Horizon Europe · Avrupa Birliği

Leveraging functional genomics to reveal novel targets for cancer treatment

10 Şubat 2027 tarihinde açılıyor

AB Ufuk Avrupa programı tarafından 4 hibe bekleniyor; proje başına €7 milyon – €8 milyon; toplam bütçe €32,32 milyon. Başvurular 16 Eylül 2027 tarihinde kapanıyor (AB çağrıları genellikle Brüksel saatiyle 17:00’de kapanır). AB üye ülkelerindeki ve Türkiye gibi ortak ülkelerdeki kuruluşlar genellikle katılabilir; konu koşulları belirleyicidir.

Son başvuru
16 Eylül 2027 (305 gün kaldı)
Açılış
10 Şubat 2027
Hibe tutarı
Proje başına €7 milyon – €8 milyon
Toplam bütçe
€32,32 milyon
Destek oranı
Uygun maliyetlerin %100’ü Bu program için standart kural; çağrı farklı olabilir.
Toplam bütçe
€32,32 milyon
Beklenen hibe sayısı
4
Faaliyet türü
HORIZON Research and Innovation Actions · HORIZON Action Grant Budget-Based
Olası başvuru sahipleri
Şirketler, KOBİ’ler / girişimler, Kâr amacı gütmeyenler, Üniversiteler ve araştırma, Kamu kurumları Kaynak kategorilerinden veya program kurallarından; uygunluğa çağrı karar verir.
Fon sağlayıcı
Horizon Europe (HORIZON)
Referans
HORIZON-MISS-2027-02-CANCER-01
Çağrı
HORIZON-MISS-2027-02
Son kontrol
14 Kasım 2026

Resmi çağrıyı aç ↗ Son tarihi takvime ekle

Resmi açıklamalar fon sağlayıcının dilindedir (çoğunlukla İngilizce); bu sayfadaki özet ve temel bilgiler Türkçedir.

Beklenen sonuçlar

Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes:

• Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets.

• Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments.

• Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data.

Kapsam

The proposed topic will contribute to the EU Cancer Mission objective of improving the understanding of cancer initiation and progression. Of particular interest for this topic are paediatric and adolescent cancers [1] , cancers with limited treatment options, refractory cancers, rare cancers or cancer types with low five-year survival rates. Proposals may include the design of exploratory mechanistic studies using longitudinal patient bio-samples, clinical proof-of-concept studies and/or observational and translational studies involving newly collected or existing data, as appropriate. Applicants are encouraged to leverage technological advances in functional genomics [2] and structural biology including but not limited to rapid gene sequencing, single-cell studies, spatial gene mapping, spatial transcriptomics, epigenetic profiling, liquid biopsies and functional precision oncology pipelines. The use of causal inference, computational modelling and/or artificial intelligence tools is encouraged for the collection, visualisation, analysis and management of large, complex, and heterogeneous data sets. Collaboration among different scientific disciplines, including healthcare professionals, is envisaged [3] .

Tam metni oku

Applicants should address all of the following activities:

• To identify and validate new targets for innovative therapeutic approaches, by developing experimental models [4] and technologies to access the functional effects of tumour temporal heterogeneity on disease initiation, progression and relapse.

• To investigate the mechanisms underlying the interply between the tumor’s dynamic multi-omics characteristics, its microenvironment and patient specific factors [5] during disease initiation and progression. This includes elucidating the mechanisms of adaptive resistance to therapies, utilizing clinical data where appropriate [6] .

• To apply state-of-the-art approaches, tools and models to integrate and analyse FAIR (Findable, Accessible, Interoperable, Reusable) multimodal longitudinal patient data. These digital assets should be made available through the UNCAN.eu research platform. All datasets produced should be described with metadata records in the EU dataset catalogue of the European Health Data Space. The involvement of existing ESFRI research infrastructures offering life science resources [7] including biobanking options should be appropriately reflected in the proposal workplan.

Advantage should be taken to the extent possible of data and experience gained under current large-scale initiatives such as: the European 1M+ Genomes [8] and the European Cancer Imaging initiative [9] and others as appropriate. Successful proposals are expected to establish appropriate collaborations with the project UNCAN-CONNECT that is implementing the UNCAN.eu research platform [10] .

Successful proposals will be asked to join the 'Understanding' project cluster of the Cancer Mission [11] and should include a budget for networking, attendance at…

Kimler başvurabilir

Consortium of at least 3 independent legal entities from 3 different EU Member States or associated countries, at least one in a Member State (Horizon Europe standard rule).

Başvuru sahibi kategorileri yalnızca bir başlangıç noktasıdır. Uygunluğa resmi çağrı karar verir.

Konular

Anticancer therapy Cancer and its biological basis Epigenetics and gene regulation Genomics, comparative genomics, functional genomics Cancer onset Cancer progression Functional Genomics Therapeutic targets

Zamanlama

Single-stage call. Next deadline 2027-09-16. The portal states the exact cut-off time (EU calls usually close at 17:00 Brussels time).

Nasıl başvurulur

  1. Portaldaki konunun tamamını okuyun: beklenen sonuçlar, kapsam, faaliyet türü ve ülke veya konsorsiyum kısıtlamaları dahil uygunluk koşulları.
  2. Kuruluşunuzu AB Funding & Tenders Portalına kaydederek her ortak için bir PIC numarası alın.
  3. İşbirliğine dayalı araştırma ve yenilik projeleri genellikle üç farklı AB üye ülkesi veya ortak ülkeden en az üç bağımsız ortak gerektirir (Türkiye Ufuk Avrupa’ya ortak ülkedir). Bu konudaki kuralı doğrulayın.
  4. Bölüm A’yı (portalda doldurulan idari formlar ve bütçe) ve Bölüm B’yi (bu faaliyet türü için resmi şablondaki teknik açıklama) hazırlayın.
  5. Son başvuru günü kapanış saatinden önce portal üzerinden gönderin. Geç başvurular kabul edilmez.

From the call text

Who can apply
Not stated in the call text we hold — check the official page
Company stage
Not stated in the call text we hold — check the official page
Single applicant or consortium
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.
Where applicants must be based
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.
Where to apply
Read the topic conditions on the EU Funding & Tenders Portal for eligible countries, consortium requirements, budget and the application route.

AB başvuru rehberini okuyun

Resmi kaynaklar

Resmi çağrı sayfası

Bu sayfadaki bilgiler resmi kaynaktan alınmıştır ve en son 14 Kasım 2026 tarihinde kontrol edilmiştir. Sonraki değişiklikler dahil, fon sağlayıcının kendi belgeleri her zaman önceliklidir.

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